Specialty Solvents

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Cyclopentyl Methyl Ether (CPME)

Processing Advantages for Pharmaceuticals

Cyclopentyl Methyl Ether (CPME) offers high hydrophobicity, high boiling point and low heat of vaporization unlike common ether solvents THF, MTBE, and dioxane. Its low peroxide formation, high resistance to acids and bases and narrow explosion range improve safety during synthesis, extraction and crystallization of pharmaceutical active ingredients.

Formula: C₆H₁₂O

Molecular Weight: 100.16 g/mol

Characteristics: High hydrophobicity, wide liquidity range, low heat of vaporization, low peroxide formation, narrow explosion area, stable to acids and bases, easy drying.

Availability: 16 kg can, 170 kg drum, and ISO tank container.

High Boiling Point and Low Heat of Vaporization

CPME's high boiling point enable a higher temperature processing window. Its low heat of vaporization enables easy solvent recovery and purification, decreasing the energy required for dehydration and solvent collection.

High Hydrophobicity

CPME has both very low solubility in water, and also very low solubility of water in CPME. Minimizing contaminating water content during synthesis helps prevent unwanted hydrolysis of sensitive active ingredients and prevents quenching of synthetic chemical reagents (i,.e metal hydrides used in Grignard reactions).

Improved safety

CPME's narrow explosion range and resistance to peroxide formation help prevent dangerous chemical reactions. In addition, the improved solubility of reaction intermediates in CPME eliminates the need for toxic or highly reactive solvents while also minimizing the number of steps in complex synthesis processes.

Cyclopentanone (CPN)

High Purity Solvent for Semiconductor Processing

Cyclopentanone (CPN) excels at dissolving polymers such as polyimide and can withstand high temperatures and prolonged processing. Its high purity helps minimize trace impurities during semiconductor processing, supporting high-performance manufacturing.

Formula: C₅H₈O
Molecular Weight: 84.12 g/mol
Characteristics: High boiling point, stable under standard conditions, versatile solvent with low viscosity, exhibits good solubility for various compounds, key intermediate for industrial chemical synthesis.

Availability: 18 kg can, 180 kg drum (steel or HDPE), ISO tank container

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High Solvency

Polyimide and other polymers are highly soluble in CPN. In addition to its use in photosensitive polyimide developers, it can also be used as a coating solvent for OLED applications.

High Process Stability

CPN's high boiling point of ~130 ^oC gives it a balance between processing stability at elevated temperatures vs. drying ability. CPN exhibits faster evaporation rates than other high-boiling solvents like N-methylpyrroiridone (NMP) and gamma-butyrolactone (GBL), making it better suited for applications that require quick drying.

High Purity

CPN's high purity results in fewer metal impurities during semiconductor processing, critical for improving manufacturing yields and delivering devices with long-term reliability.

Name	Cyclopentylmethyl Ether (CPME)	Cyclopentanone (CPN)
Group	ether	ketone
Structure
Molecular weight	100.16 g/mol	84.12 g/mol
Boiling point	106 °C	131 °C
Density	0.86g/cm³ (25°C)	0.95 g/cm³ (15~20 °C)
Melting point	< -140 °C	-58.2 ~ -51 °C
Surface tension	25.17 mN/m (20 °C)	33.42 mN/m (25 °C)
Specific heat	1.818 kJ/(kg.K) (25 °C)	1.824 kJ/(kg.K) (25 °C)
Vaporization energy	290 kJ/kg	403 kJ/kg
Viscosity	0.569 mPa.s (25 °C)	1.075 mPa.s (25 °C)
Flash point	-1 °C	26 ~ 30 °C
Applications	Industrial chemistry process solvent (reactions, extractions); coating solvent	Developer for photoresists; solvent for adhesives and polymers, solvent for synthesis of fragrances and pharmaceuticals

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