Syringes

ZEONEX^® and ZEONOR^® Cyclo Olefin Polymers

Advanced Polymer Resin for Medical Precision

ZEONEX^®and ZEONEX^® Medical Grade resins for molding high-performance injectables ensure exceptional strength, clarity, and drug compatibility for critical healthcare applications. Medical-grade resins ZEONEX^® 690R, 790R, 5000 and ZEONOR^® 1020R have been assessed for compliance with USP Class VI and <661.1>, ISO 10993, and JP and EU standards. Drug master file information is available upon request.

Technical Data Sheet

Low Protein Adsorption and Aggregation

ZEONEX^® and ZEONOR^® are optimal for long-term storage of protein and peptide-based biopharmaceuticals. Compared to glass and polypropylene, ZEONEX^® and ZEONOR^®'s low zeta potential and inert surface result in very little protein adsorption. Elimination of silicone oil from the syringe barrel further reduces adsorption and potential protein aggregation. ZEONEX^® and ZEONOR^® do not contribute to pH shift of the diluent, common with glass, thus reducing the chance for protein precipitation

Line graph showing protein adsorption of Abatacept on glass or ZEONEX® 690R syringes. X-axis: concentration (mg/mL). Y-axis: protein adsorbed (mg/m²).

Low Moisture Permeability

ZEONEX^® and ZEONOR^® demonstrate a high moisture barrier property compared to conventional polymers. This barrier minimizes evaporation during storage, maintaining stable reagent concentrations. The barrier provided by ZEONEX^® and ZEONOR^® also helps prevent degradation of moisture-sensitive compounds, extending the shelf life of pharmaceuticals.

Durability

ZEONEX^® and ZEONOR^®excel for drug storage devices where there is breakage risk. Compared to glass and Polypropylene (PP), syringes made from ZEONEX^® and ZEONOR^® exhibit superior impact strength over a wide range of temperatures, including cryogenic storage conditions (-194 °C). ZEONEX^® and ZEONOR^® are also mechanically tough and withstand increased stress from injecting viscous drug formulations or from auto-injector syringes with high injection forces.

Sterilization compatibility

ZEONEX^® and ZEONOR^® syringes are compatible with EtO, Gamma irradiation, peroxide, and steam/autoclave* sterilization methods. Compared to other plastics, ZEONEX^® and ZEONOR^® have lower post-sterilization haze, enabling easier visual inspection of syringe contents. The material strength and durability are also maintained post-sterilization.

*Grades ZEONEX^® 690R and 790R are compatible with steam/autoclave sterilization

Manufacturing

ZEONEX^® and ZEONOR^® have excellent injection molding properties, suitable for standard geometries as well as precision micro-molding. The superior mechanical strength and flexural modulus of ZEONEX^® and ZEONOR^® make these resins ideal for manufacturing complex designs, such as in Wearables, that have a high risk of breakage when releasing from the mold.

Industries

Precision Polymer for Unmatched Performance

We’ve got what you need – premium resins that power innovation, support compliance and improve product performance for major companies in Pharma, Medtech, Research, and Diagnostic sectors.